Animal models of prenatal immune challenge and their contribution to the study of schizophrenia: a systematic review

Prenatal immune challenge (PIC) in pregnant rodents produces offspring with abnormalities in behavior, histology, and gene expression that are reminiscent of schizophrenia and autism.Based bg tuley on this, the goal of this article was to review the main contributions of PIC models, especially the one using the viral-mimetic particle polyriboinosin

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